Download EBOOK Her-2: The Making of Herceptin, a Revolutionary Treatment for Breast Cancer PDF for free


Download EBOOK Her-2: The Making of Herceptin, a Revolutionary Treatment for Breast Cancer PDF for free Category: Health
The author of the book: Robert Bazell
Format files: PDF, EPUB, TXT, DOCX
The size of the: 22.98 MB
Language: English
ISBN-13: 9780812991840
Edition: Random House Inc
Date of issue: 25 August 1998

Description of the book "Her-2: The Making of Herceptin, a Revolutionary Treatment for Breast Cancer":

Two years after she underwent a mastectomy and chemotherapy, Barbara Bradfield's aggressive breast cancer had recurred and spread to her lungs. The outlook was grim. Then she took part in Genentech's clinical trials for a new drug. Five years later she remains cancer-free. Her-2 is the biography of Herceptin, the drug that provoked dramatic responses in Barbara Bradfield and other women in the trials and that offers promise for hundreds of thousands of breast cancer patients. Unlike chemotherapy or radiation, Herceptin has no disabling side effects. It works by inactivating Her-2/neu--a protein that makes PDF cancer cells grow especially quickly-- produced by a gene found in 25 to 30 percent of all breast tumors. Herceptin caused some patients' cancers to disappear completely; in others, it slowed the progression of the disease and gave the women months or years they wouldn't otherwise have had. Herceptin is the first treatment targeted at a gene defect that gives rise to cancer. It marks the beginning of a new era of treatment for all kinds of cancers. Robert Bazell presents a riveting account of how Herceptin was born. Her-2 is a story of dramatic discoveries and strong personalities, showing the ePub combination of scientific investigation, money, politics, ego, corporate decisions, patient activism, and luck involved in moving this groundbreaking drug from the lab to a patient's bedside. Bazell's deft portraits introduce us to the remarkable people instrumental in Herceptin's history, including Dr. Dennis Slamon, the driven UCLA oncologist who played the primary role in developing the treatment; Lily Tartikoff, wife of television executive Brandon Tartikoff, who tapped into Hollywood money and glamour to help fund Slamon's research; and Marti Nelson, who inspired the activists who lobbied for a compassionate use program that would allow women outside the PDF clinical trials to have access to the limited supplies of Herceptin prior to FDA approval of the drug. And throughout there are the stories of the heroic women with advanced breast cancer who volunteered for the trials, risking what time they had left on an unproven treatment. Meticulously researched, written with clarity and compassion, Her-2 is masterly reporting on cutting-edge science. From the Hardcover edition.

Download EBOOK Her-2: The Making of Herceptin, a Revolutionary Treatment for Breast Cancer PDF for free


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Robert Bazell

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Download EBOOK Her-2: The Making of Herceptin, a Revolutionary Treatment for Breast Cancer PDF for free



Download EBOOK Her-2: The Making of Herceptin, a Revolutionary Treatment for Breast Cancer for free

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