Download EBOOK The Role of Onion Extracts in the Prevention of Stroke PDF for free


Download EBOOK The Role of Onion Extracts in the Prevention of Stroke PDF for free Category: Medical
The author of the book: Richa Shri
Format files: PDF, EPUB, TXT, DOCX
The size of the: 986 KB
Language: English
ISBN-13: 9783844302363
Edition: LAP Lambert Academic Publishing
Date of issue: 20 February 2011

Description of the book "The Role of Onion Extracts in the Prevention of Stroke":

Stroke is the second leading cause of death in the world. Ischemic stroke is characterized by rapid onset of neurological injury due to interruption of blood flow to the brain. Free radicals have been implicated in cerebral ischemia and reperfusion- induced neuronal injury. Hence anti-oxidants have shown neuroprotective effect.The present study investigates the effect of methanolic extracts of a natural anti-oxidant plant - Allium cepa on ischemia and reperfusion induced cerebral injury. Global cerebral ischemia was induced by bilateral carotid artery occlusion for 10 min followed by reperfusion for 24 hr. Cerebral infarct size was estimated using triphenyltetrazolium chloride staining PDF. TBARS assay was employed to measure oxidative stress. Elevated plus maze was employed to evaluate short-term memory. Motor incoordination was evaluated using inclined-beam walking test.Pretreatment with onion extracts reduced cerebral infarct size, attenuated impairment in short term memory and motor coordination along with a decrease in mitochondrial TBARS. Hence, antioxidant plant extracts that attenuate cerebral injury may play an important role in neuroprotection.

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Richa Shri

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Download EBOOK The Role of Onion Extracts in the Prevention of Stroke PDF for free



Download EBOOK The Role of Onion Extracts in the Prevention of Stroke for free

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