Download EBOOK Sickle Cell Disease PDF for free


Download EBOOK Sickle Cell Disease PDF for free Category: Medical
The author of the book: Graham R. Serjeant
Format files: PDF, EPUB, TXT, DOCX
The size of the: 23.58 MB
Language: English
ISBN-13: 9780192630360
Edition: Oxford University Press
Date of issue: 1 June 2001

Description of the book "Sickle Cell Disease":

Sickle cell disease was recognized to have a molecular basis more than 50 years ago, since when knowledge of the pathophysiology of the disease has paralleled the developments of molecular biology. Characterized by a striking red cell deformity, a great deal has been learnt about the mechanisms involved and animal models developed over the last 10 years have contributed to these studies. Despite greater understanding of the molecular mechanisms, this knowledge has had little impact in improving management at the bedside. It is the authors' belief that much of importance remains to be learnt from clinical studies which ultimately may define the PDF questions most relevant for our molecular colleagues to answer. Jamaica has provided a superb setting for clinical studies, which initially documented the extremely variable clinical course and then proceeded to seek the determinants in a Cohort Study based on newborn diagnosis and follow-up which has continued for the past 27 years. This new edition of Sickle Cell Disease reviews the history and many of the recent developments in laboratory studies but retains the perspective of a practising clinician. A critical appraisal of the available observations and evidence has sought to define the best practice in its management.

Download EBOOK Sickle Cell Disease PDF for free


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Graham R. Serjeant

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Download EBOOK Sickle Cell Disease PDF for free



Download EBOOK Sickle Cell Disease for free

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