Download EBOOK Sphingosine-1-Phosphate Signaling in Immunology and Infectious Diseases PDF for free


Download EBOOK Sphingosine-1-Phosphate Signaling in Immunology and Infectious Diseases PDF for free Category: Medical
The author of the book: Michael B. A. Oldstone
Format files: PDF, EPUB, TXT, DOCX
The size of the: 28.64 MB
Language: English
ISBN-13: 9783319058788
Edition: Springer International Publishing AG
Date of issue: 29 April 2014

Description of the book "Sphingosine-1-Phosphate Signaling in Immunology and Infectious Diseases":

This volume focuses on the role of sphingosine-1-phosphate (S1P) and its analogs in the induced sequestration of lymphocytes in secondary lymphoid organs or in the microenvironment of tissues involved in infection or autoimmune disease. Initial chapters define the pathways to understand S1P signaling. They cover the organization of signaling systems, the structural biology of the S1P1 receptor, and the chemical and genetic tools that are available and useful to explore this area of research and therapeutics. The later chapters highlight S1P and endothelial integrity, lymphocyte migration in the spleen, and S1P agonist in PDF controlling immunopathologic manifestations of acute respiratory influenza virus infection (in the lung), and its accompanying cytokine storm as well as immunopathologic disease of the central nervous system, including the beginning of treatments in multiple sclerosis. One chapter reveals the possible involvement of other lipid molecules, their use for better understanding lipid signaling, and their potential in the modulation of immune responses.

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Michael B. A. Oldstone

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Download EBOOK Sphingosine-1-Phosphate Signaling in Immunology and Infectious Diseases PDF for free



Download EBOOK Sphingosine-1-Phosphate Signaling in Immunology and Infectious Diseases for free

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