Download EBOOK Increasing the Immuno-Stimulatory Capacity of Human Leukemia Cells PDF for free


Download EBOOK Increasing the Immuno-Stimulatory Capacity of Human Leukemia Cells PDF for free Category: Medical
The author of the book: Evelien Smits
Format files: PDF, EPUB, TXT, DOCX
The size of the: 658 KB
Language: English
ISBN-13: 9783845442471
Edition: LAP Lambert Academic Publishing
Date of issue: 22 September 2011

Description of the book "Increasing the Immuno-Stimulatory Capacity of Human Leukemia Cells":

The ultimate goal of tumor immunotherapy is the eradication of tumor cells by the immune system. Immunotherapy for leukemia is a promising targeted strategy to prevent relapse and to prolong the survival of leukemia patients by eliminating residual leukemic cells that survive standard therapy. However, in order to elicit effective immune responses during immunotherapy, the immune tolerance against leukemic cells needs to be broken. Mechanisms that contribute to immune tolerance are the lack of expression of costimulatory molecules by leukemic cells and the lack of danger signals in leukemic cells and/or in their microenvironment. Here, we studied the ability PDF of RNA molecules or synthetic derivatives to increase the immunogenicity of acute myeloid leukemia (AML) cells and to break the non-responsiveness of immune cells to AML cells, in the light of their potential future use in leukemia immunotherapy strategies.

Download EBOOK Increasing the Immuno-Stimulatory Capacity of Human Leukemia Cells PDF for free


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Evelien Smits

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Download EBOOK Increasing the Immuno-Stimulatory Capacity of Human Leukemia Cells PDF for free



Download EBOOK Increasing the Immuno-Stimulatory Capacity of Human Leukemia Cells for free

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